EXPLICIT MOLECULAR DYNAMICS SIMULATION STUDIES TO DISCOVER NOVEL NATURAL COMPOUND ANALOGUES AS MYCOBACTERIUM TUBERCULOSIS INHIBITORS

Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors

Tuberculosis (TB) in one of the dreadful diseases present globally.This is caused by Mycobacterium tuberculosis.Mycobacterium tuberculosis dethiobiotin synthetase (MtDTBS) is an essential enzyme in biotin biosynthesis and is an ideal target to design and develop novel inhibitors.In order to effectively combat this disease six natural compound (bute

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SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts.

Since the first case of COVID-19 in December 2019 in Wuhan, China, SARS-CoV-2 has spread worldwide and within a year and a half has caused 3.56 million deaths globally.With dramatically increasing infection numbers, and the arrival of new variants with increased infectivity, tracking the evolution of its genome is crucial for effectively controllin

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Techno-Economic and Risk Assessment of Small-Scale LNG Distribution for Replacing Diesel Fuel in Nusa Tenggara Region

The conversion of existing diesel-fuel power plants in remote areas of Indonesia to gas is a practical solution for the reduction of carbon emissions.However, the transportation of natural gas from its sources to plant gates across the vast and dispersed islands of the Indonesian archipelago using small-scale Liquefied Natural Gas (LNG) poses chall

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Dendritic cells and their relation to apical peridontitis

Abstract: The purpose of this manuscript was to re-discuss apical periodontitis, eve audio sc208 apical biofilm, and its possible relationship with dendritic cells (DC).DCs are potent regulators of the immune system and their function is divided into three categories that involve the presentation of antigens: the presentation of antigens and activa

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